Genus Lophophora

Lophophora is a genus of spineless, button-like cacti native to the southwestern United States through Northeast Mexico and South to Querétaro in central Mexico.

Species in the genus Lophophora of plants

Peyote - Lophophora williamsii , better known by its common name Peyote , is a small, spineless cactus with psychoactive alkaloids, particularly mescaline.